BDBM370225 US10233188, Example 112::US10800783, Example 112::US11396512, Example 112
SMILES Cc1cc2cnc(NC3CCN(CC3)S(=O)(=O)C3CC3)nc2n([C@@H]2CCC[C@@]2(C)O)c1=O
InChI Key InChIKey=ZGBMIKQTQVROES-XMSQKQJNSA-N
Data 6 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 370225
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Homo sapiens (Human))
Pfizer
US Patent
Pfizer
US Patent
Affinity DataKi: 1.24nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair